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Notably, just next to this position, the substitution of Met442 in H. sapiens BChE by Ala440 in O. latipes BChE results in a significantly widened choline binding pocket.
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The Dodd-Frank financial regulatory overhaul significantly widened their mandates, calling for a crackdown on everything from the derivatives industry to executive compensation.
CEO Tim Koogle last week told a gathering of technology industry executives in Monte Carlo that the popular portal has significantly widened its lead in terms of page views, to 385 million a day from 310 million a day in March.
Drawings were significantly widened and deepened, and considered from an infinite number of different angles.
Station Road was significantly widened and rerouted slightly in 1967 in a further attempt to accommodate increasing traffic.
In 4-day and 7-day groups, the airway epithelial cells underwent obvious necrosis with a large number of inflammatory cell infiltrations, alveolar septa were significantly widened with hyperemia, and perivascular spaces were also filled with inflammatory cells).
Enantioselective hydrolysis of ester and amide bonds catalyzed by lipases, esterases, and proteases represents a landmark in biotransformations.[ 1] Their (industrial) application was significantly widened by introduction of dynamic resolution concepts that make use of in situ racemization[ 2] to overcome the 50 %-yield threshold of kinetic resolution.
Even considering only class A motifs we predicted about one hundred novel DYNLL partners and this way significantly widened the scope of the human interactome around DYNLL.
The new political climate has significantly widened their agenda.
Colleges have gotten away with this in large part because the gap in earnings between people with and without degrees significantly widened during that time.
The deaths of 76 workers – 64 from Sellafield and 12 from other UK nuclear plants – were examined, although the scope of the inquiry was later significantly widened.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com