Sentence examples for a significantly reduced effect from inspiring English sources

Compared to natural cyclopamine, these cyclopamine isomers have a significantly reduced effect on the ciliary transport of the Hh receptor smoothened, and reduced inhibition on the Hedgehog signaling pathway.

In contrast, co-expression of R-Ras and FLNaΔ3 had a significantly reduced effect on migration.

Free GDNF had a significantly reduced effect in comparison to the conjugated-GDNF.

However, eQTLs tend to have significantly reduced effect sizes on protein levels, which suggests that their potential impact on downstream phenotypes is often attenuated or buffered.

Previously, we found that TZQ-F showed significantly reduced effects on serum glucose (GLU) and triglyceride (TG) levels in high- carbohydrate/ high- fat diet rats [ 11] and genetic type 2 diabetes model KK-Ay mice [ 12].

As shown in Fig. 2, the culture supernatants of S. aureus grown in the presence of increasing concentrations of perilla oil showed a significantly reduced stimulatory effect on T-cell proliferation.

Those patients who are inadvertently underdosed are at risk of a significantly reduced anticancer effect.

Also knockdown of targets in the PI3K signaling cascade (IRS1, PI3KCA and AKT2) had a significantly reduced proliferative effect in all cell lines.

On the other hand, during an insulin tolerance test, the two MSG-treated groups had a significantly reduced response to the hypoglycaemic effects of insulin, when compared with P-P and P-7 groups (p<0.05) (Figure 1D), indicating a state of insulin resistance.

Ding et al. found that RG7388 activates p53 at a significantly reduced concentration than RG7112, and this effect was seen both in vitro and in vivo.

In the 'full' model (adjusted for age, survey, lifestyle, clinical and psychosocial variables), male moderate drinkers still had a significantly reduced mortality risk with a comparable effect (HR: 0.74; 95% CI: 0.58-0.94, p = 0.002).