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As compared to "non-tolerant" rats, the depressive effect of morphine was weaker in "morphine-tolerant" animals where the threshold did not change following morphine but the gain of the stimulus-response curve decreased, albeit to a significantly lesser extent than in the "non-tolerant" group.
The Ino80 and Ies2 subunits also bind to the H2A-H2B dimer, but to a significantly lesser extent than Arp5.
Several other factors were up-regulated, but to a significantly lesser degree.
Lung weights increased in both groups, but to a significantly lesser extent in p110β-RBD-DM p110β-RBD-DM p110β-RBD-DM
This was also shown with anastrozole, but to a significantly lesser extent [ 3, 48].
Males were affected to a significantly lesser degree, however (Fig. 1).
The enoximone group exhibited a significantly lesser increase in HR and a greater increase in stroke index than did either the dopamine or dobutamine group, and also exhibited significantly a greater increase in CI and decrease in SVR in comparison with dopamine.
Lower concentrations of dissolved silica species (0.2 mM) led to a lesser decrease (70%) in iron reactivity toward 1,1,1-TCA.
Morphological observations also supported a lesser decrease of TH-immunoreactivity in both SNpc and SNpr.
Interestingly, a lesser decrease in cortisol is observed in patients with depression.
Patients who had ⩾62% CYFRA 21-1 reduction survived 14 vs 6.6 months for those who had a lesser decrease (P=0.02).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com