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The phrase "a significant violation" is correct and usable in written English.
It can be used in contexts where you are discussing breaches of rules, laws, or standards that are considered important or serious.
Example: "The committee found that there had been a significant violation of the safety regulations, which could have endangered the workers."
Alternatives: "a major breach" or "a serious infraction."
Exact(17)
Because Mauchly's test of sphericity indicated a significant violation of the assumption of sphericity (P < 0.0001), significance levels for within-subject effects were calculated using a Greenhouse Geisser correction of the degrees of freedom [ 54].
"To be in contempt, there has to be a significant violation.
Jonas Christoffersen, of the Danish Institute for Human Rights, said this was a "significant violation" of human rights for refugees.
In addition, RCAs are now required to "take action to stop the violation" when they encounter a "significant violation" of University rules.
They all escaped the added oversight, which would have allowed the federal government to close down the mines every time they found a significant violation.
"The detention of children as 'enemy combatants' and their interrogation without even the basic safeguards to which they were entitled was a significant violation of human rights," William F. Schulz, executive director of Amnesty International U.S.A., said in a statement.
Similar(43)
Prolonged artillery fire was heard late on Saturday to the east of the port of Mariupol in eastern Ukraine, a Reuters reporter said, in what may be the first significant violation of a ceasefire declared little more than 24 hours earlier.
We are trying to find their bodies to return them to their mothers for burial". Prolonged artillery fire was heard late on Saturday to the east of the port of Mariupol in eastern Ukraine, a Reuters reporter said, in what may be the first significant violation of a ceasefire declared little more than 24 hours earlier.
Another activist who was at the heart of the Tahrir Square protests in February, Mosa'ab Elshamy, reported that he witnessed, "no significant violation in Zamalek," an upscale part of Cairo.
They will not go along with a unilateral act by the U.S. president and let all the past progress go to waste, and risk their newly established business opportunities in Iran, without a significant Iranian violation of the deal, which is not likely to happen.
Potential interactions were identified for subgroups defined by presence versus absence of a significant protocol violation (P = 0.07), original versus amended protocol (P = 0.08), and APACHE II quartile at baseline (P = 0.09).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com