Sentence examples for a significant variant of from inspiring English sources

Globally, approximately 5% of the population is a carrier of a significant variant of haemoglobin disorders with as many as 40% carriers in some regional populations (Modell and Darlison 2008).

There are significant variants of each of these.

Being unable to report a clinically significant variant due to a failure of the Sanger technology introduces a challenging obstacle if the NGS assay is analytically validated.

The conformational changes observed at aa positions 297, 298, 394 and 395 coincided with the appearance of an epidemiologically significant variant and antigenic cluster transition (Table 1 and Table 2).

The goal of a low-frequency variant collapsing analysis is to compare the variant burden between two groups and identify bins with a significant excess of variants in one group compared to another.

Such interpretation is important, as a significant proportion of variants are unclassified (upwards of 50% of variants) (17).

Conversely, there were a significant number of variants in our data that were unanimously called by the five Illumina variant-calling pipelines but not by the CG WGS.

Sequenced genomes of mutagenized strains contain a substantial number of variants (on average more than 300 variants per chromosome, about 30 of which are in protein coding sequences) and a significant number of variants remain after outcrossing and/or may even be introduced by outcrossing [5].

Multiple genome-wide and targeted association studies reveal a significant association of variants in the CHRNA5-CHRNA3-CHRNB4 (CHRNA5/A3/B4) gene cluster on chromosome 15 with nicotine dependence.

In summary, we are the first to reveal a significant association of variants in CRHR1 with ND.

A significant association of variants in RRP1B with metastasis-free survival was observed (P = 0.012), validating the role of RRP1B with inherited metastatic susceptibility.