The phrase "a significant usage of" is correct and usable in written English.
It can be used when discussing the extent or frequency of something being used, particularly in academic or analytical contexts.
Example: "The study revealed a significant usage of renewable energy sources in urban areas over the past decade."
Alternatives: "a considerable amount of" or "a notable application of".
Nonetheless, these industrial processes exert some of the most profound impacts on the ecosystem because of the significant usage of natural resources, the environmental discharges associated with the processing, and the ecological effects of the products.
X-Play, however, considered the graphics "underwhelming," criticizing the lack of significant usage of animation and cinematic scenes, and remarking that the graphics "follow the rest of the game's lead".
At least six Central European countries (Hungary, the Czech and Slovak Republics, Croatia, Slovenia, Romania) have shown some interest in salt fluoridation; however, significant usage of approximately 35% was only achieved in the Czech Republic.
Comparative analysis of the total brain samples resulted in the identification of five genes (CANX, DNAJC5, MGEA5, TMEM66, WDR92) with statistically significant usage of alternative promoters in AD samples (p<0.05 and passing false discovery rate threshold).
Recent studies recorded significant usage of CAM in community paediatrics; 32% of children newly diagnosed with autism; 54% with behavioural problems and 56% in families of children with cerebral palsy [ 5- 7].
Consistently, in cis knockdown of KAT5 by deleting a core binding motif of transcription factor (E2F3) using CRISPR/Cas9 approach led to a significant lower usage of distal pA site of RNASEH2C (Fig. 2E).
Intriguingly, unlike in trans overexpression of NAT, in cis elevation of NAT caused a significant higher usage of distal pA site in RNASEH2C by both qRT-PCR and Northern blot (Figs. 2D and S6).
There was a significant different usage of training equipment between the private and public sector companies (P = 0.002).
Ninety-eight prokaryotic genomes have Z scores larger than 3.0, indicating that 72% of the genomes have significant usage bias of successive synonymous codons.
