Sentence examples for a significant upfront from inspiring English sources

A significant upfront investment in research and development is a prerequisite in the commercialization of biosensors.

They can have a significant upfront cost, but can also have a quick payback and generate savings that can be further invested.

This implies a significant upfront faculty investment, including carefully designing the syllabus and structuring the weekly exercises, so that they build upon one another.

To start, institutions increasingly have come to understand the activist is sincere in its belief about problems at the "target," since it has made a significant upfront investment and has a business model that depends upon repeated successful engagements.

The companies promise to save borrowers' homes from foreclosure in exchange for a significant upfront fee, often thousands of dollars, but consumers often end up worse off than when they started.

It can take as many as four years for coffee plants to get established, said Mark Gaskell, a farm adviser in the University of California system, meaning a grower must make a significant upfront investment before seeing any return.

And so the only way to do this effectively usually is with a fairly significant upfront investment and building any demands whatsoever, and then providing services and products at extremely low margins with the necessity of reaching high volumes of individuals.

Despite recent progress, setting up and maintaining a data integration application still requires significant upfront effort of creating a mediated schema and semantic mappings from the data sources to the mediated schema.

This has limited the use of such technology in pre-clinical research where prolonged and constant exposure is needed to validate targets with less-than-ideal tool compounds to enable a data driven decision without significant upfront investment.

Many organizational leaders have a mental model that learning requires significant upfront investment to develop the course materials and take people out of their work so that they can go to the training program and learn.

AD is associated with significant upfront costs but is a very effective intervention, limited most frequently by the ability to timetable visits.