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The phrase "a significant target for" is correct and usable in written English.
It can be used when discussing something that is a major focus or objective for a particular action or strategy.
Example: "The new marketing campaign aims to establish a significant target for increasing brand awareness among young consumers."
Alternatives: "a major focus for" or "a key objective for".
Exact(21)
A student movement demanding sweeping political change is surging in popularity and is now a significant target for attack by the government of the Yugoslav president, Slobodan Milosevic.
A1 Yugoslavia Wary of Students Otpor, a Serbian student movement demanding sweeping political change, is surging in popularity and is now a significant target for attack by the government of the Yugoslav president, Slobodan Milosevic.
Since in the scientific and technical literature multiple, sometimes incompatible, definitions of 'measurement' can be found, identifying a single conceptual framework is a significant target for measurement science, towards a generalized concept of measurement, in compliance with the notion of widely-defined measurement proposed by Ludwik Finkelstein.
McAfee Labs says that URL-shortening services, which create more than 3,000 URLs per minute, will be a significant target for cyber criminals in 2011.
The OPRM1 receptor is the site of action for many endogenous opioid peptides and a significant target for opioid analgesics [18, 19].
We're a significant target for attackers out in the marketplace, and one of my objectives as a leader of the company is to reduce our overall risk.
Similar(39)
The gene encoding MMP-13 was not identified as a significant target of leptin for chondrocytes originated from normal or overweight patients.
TLR4 signalling may therefore represent a significant target molecule for the design of specific inhibitors as a novel therapeutic agent to AMI.
Lastly, the interaction of Letter targetness × Orientation (F[1,12] = 5, p < 0.04) and relative post-hoc comparisons evidenced a significant target effect for standard (target = 1.84; non-target = 1.3 μV) but not rotated (target = 1.3; non-target = 1.46 μV) strings.
However, it remains somewhat controversial as to whether macrophages represent a significant target cell type for HIV-1 in vivo.
Neither the pattern searches nor the nucleotide distributions in the TSD indicate a significant target site preference for insertion.
More suggestions(16)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com