The phrase "a significant substitute" is correct and usable in written English.
It can be used when discussing an alternative option that holds considerable importance or value in a particular context.
Example: "In the absence of traditional methods, online learning has become a significant substitute for in-person education."
Alternatives: "an important alternative" or "a notable replacement."
Iran's president chipped in, suggesting helpfully that "Since the divine treasures are infinite, you should not worry about financial issues".So far, no significant substitute cash has made its way to Hamas.
As a consequence, there is a significant potential to substitute fossil fuels by the use of solar heat.
For example, Company X's fish and chips would tend to have a relatively high elasticity of demand if a significant number of substitutes are available, whereas food in general would have an extremely low elasticity of demand because no substitutes exist.
The correlation of the peaks and their contribution to predict models were analyzed as before, and peptides with a significant effect were substituted into the multivariate logistic regression (Table 6).
However, compared to the bone substitute materials, which are currently clinically available, there is a significant need for bone substitute materials that degrade more rapidly but at the same time stimulate osteogenesis.
However, compared to the bone substitute materials which are currently clinically available, there is a significant need for bone substitute materials which degrade more rapidly, but still stimulate osteogenesis at the same time.
Even if generative AIs get so good at dreaming up content that they could substitute a significant chunk of humanity's sweating toil, they'd still never possess the biological eyeballs required to blink forth the ad dollars the tech giants depend on.
Consistent with the time needed for any major change in energy infrastructure, another 20 30 years of sustained and aggressive growth will be required for photovoltaics to substitute a significant share of conventional energy sources.
Ultimately, land scarcity precludes the possibility of establishing plantations and energy crops to produce enough biomass to substitute for a significant fraction of fossil fuel consumption [30, 32].
