The phrase "a significant subclass of" is correct and usable in written English.
It can be used when discussing categories or groups within a larger classification, particularly in academic or technical contexts.
Example: "In the study of mammals, a significant subclass of marine mammals includes whales and dolphins."
Alternatives: "a notable category of" or "an important subset of".
In this paper, we introduce the elimination algorithm, which performs, in linear time, minimal model finding and minimal model checking for a significant subclass of positive CNF theories which we call positive head-cycle-free (HCF) theories.
Nonetheless, it is known that a significant subclass of \ \textbf{NP}\ -complete problems possess polynomial time approximation algorithms -- i.e. algorithms which are guaranteed to find a solution which is within a certain constant factor of optimality.
Pathologists reading this list may agree that the tumors from this list include clinically distinct and significant subclasses of tumors and would be welcome additions to a truly comprehensive nomenclature of neoplastic entities.
Gene expression analyses across glioblastoma multiforme tumors taken in toto has shown that there are significant subclasses of glioblastoma that differ in large ways in gene expression patterns [ 27, 32, 33].
The most significant biological function classification was in skeletal and muscular development and function with the most significant subclass being skeletal development (corrected p-value of 2.22×10−9) (Table S7).
Mammary carcinoma is a heterogeneous disease, which comprises a significant fraction of ER negative subclasses [ 38].
We define a class Father as a subclass of a class Ancestor and a class Son as a subclass of a class Descendent.
Backward selection procedure was used, with removal criterion P>0.10, to identify a subclass of significant clinical variables.
This procedure identified a subclass of significant variables among the following: treatment group (FOLFIRI vs XELIRI), age (≥60 vs <60), sex (women vs men), PS (1 2 vs 0), adjuvant chemotherapy (yes vs no), primary site (rectal vs colon), number of metastatic sites (≥3 vs 2 vs 1) and NO, OPN, TGF-β1 and VEGF-A plasma concentrations (high vs low).
Subclasses of AluS sequences provide a significant source of potential hormone response elements for retinoic acid and thyroid hormone receptors [ 36, 41].
However in this study we demonstrated a significant enhancement of both Th1 and Th2-related IgG subclasses in response to inhaled peptides and no improvement in anemia after 18 weeks of treatment.
