The phrase "a significant shortcoming" is correct and usable in written English.
It can be used to describe a notable flaw or deficiency in something, such as a plan, product, or argument.
Example: "The report highlighted a significant shortcoming in the proposed strategy that could hinder its success."
Alternatives: "a major flaw" or "a considerable deficiency."
But Ms. McCarron acknowledged that soft-shell lobster has a significant shortcoming, aside from its relatively short harvesting season.
Throughout the four-week-old trial of John A. Muhammad, the man accused of masterminding the Washington-area sniper attacks, prosecutors have had to work around what seemed a significant shortcoming in their case: most of the evidence linked only Lee Malvo, who is accused of being Mr. Muhammad's accomplice, to the killings.
A significant shortcoming of all these models is that they only regard a deterministic lead time.
Similarly, what is readily observed in implementation of an HMM is the use of various probability tables, and a significant shortcoming is revealed.
But a significant shortcoming of this method is that it neglects the sag of contact wire and cannot reflect the mechanical equilibrium relationship.
A significant shortcoming of the previous works of the SCND in fuzzy environment is that they have ignored fuzziness of decision variables.
This is a very significant shortcoming especially in practical time integration.
Considering the biological significance of DNA and particularly its role in genetic disease and tumorgenesis, this is a significant current shortcoming.
"Our inability to seize the initiative in the 'War of Ideas' with Al Qaeda is perhaps our most significant shortcoming so far in the war against terrorism," said the document, dated Sept. 17, 2003.
The most significant shortcoming is the missing distinction between various types of pluripotency, and we have started to include link annotations to distinguish these.
The only significant shortcoming in terms of specificity was the misidentification of the clinically relevant species M. marinum.
