Sentence examples for a significant sensitization to from inspiring English sources

In all children a significant sensitization to milk proteins have been documented within 2 years after vaccine reaction.

A significant sensitization to PPP was observed in the majority of cases again, except for TAP2 where MCF7 showed increased tolerance to PPP and BE showed no significant change (Table 4).

Compounds dropped from the campaign at this point consisted of those that did not reconfirm (11 compounds) and those that lacked significant sensitization to TRAIL (cell viability in the presence of the compound + TRAIL is greater than 80% of compound only-treated cells; nine compounds).

FVB mice also do not show significant sensitization to repeated doses of cocaine under our experimental conditions.

Despite the significant sensitization to TRAIL, between 8% (MDA-MB-231) and 33% (MCF-7) of the cell populations survived the combined (TRAIL/FLIPi) treatment, which suggested a differential response to this apoptotic insult by these heterogeneous cell populations.

This finding provides a 'proof of plausibility' that the LY30-induced effects of death receptor clustering, cFLIP down-regulation and ROS production are sufficient to facilitate significant sensitization to apoptosis, in cells treated with otherwise sub-lethal doses of TRAIL.

miR-511-specific anti-miR led to about 50% increase in expression of TNFR1 in livers (Fig 5A), and to a significant sensitization of B mice to TNF as measured by lethality and hypothermia (Fig 5A).

This potentiation is dependent on an interaction that can only take place in a hypoxic environment, resulting in a significant sensitization of the cells to cisplatin cell killing, with no increase in the systemic toxicity of cisplatin.

Our data showed that treatment with the adenoviral systems resulted in high-level expression of Bax and TRAIL genes directly related to apoptosis induction, leading to a significant sensitization of resistant pancreatic tumor cells.

Consistent with the model predictions, the 20 times increase of c-FLIPL levels in these HeLa-CD95 cells overexpressing short c-FLIP isoforms, led to a significant sensitization toward CD95-mediated apoptosis.

This represented a 98% reduction in tumour burden and a significant sensitization of TRAIL mediated suppression of metastatic disease.