It explains how Pinterest hit a rapid growth period in 2011 causing significant scaling challenges.
The two founders faced significant scaling challenges, from how to establish guardrails around curation of the collection to go-to-market distribution channel strategy and customer acquisition strategy.
They cost effectively sequester carbon dioxide at a significant scale.
Even something so mundane as metering of its customers becomes a significant challenge at AWscaleale.
This is a significant technical challenge at our scale, but we have a team working on it and expect to have more to share later this summer".
The large range in scales, from centimeter-scale transverse beam size and applied field scale-length, to meter-scale beam length, to kilometer-scale accelerator length, poses a significant computational challenge.
Economically-viable production of renewable transportation fuels from lignocellulosic biomass remains a significant technical challenge at the industrial scale.
Apple farmers face the same challenge as grocery shoppers, but on a more financially significant scale.
Molecular dynamics simulation has played an important role in uncovering the fundamental mechanisms of dislocation nucleation, but its limited time scale remains a significant challenge for studying nucleation at experimentally relevant conditions.
Meanwhile, the exponential growth of the protein database, the rapid generation of mass spectrometry data, and the requirement for nonspecific digestion and postmodifications in complex-sample identification also pose a significant challenge on the identification scale and speed.
The oil sands companies, however, have been scaling back as falling oil prices and the general market turmoil create a significant economic challenge for the projects.
