The phrase "a significant role when" is correct and usable in written English.
It can be used to indicate the importance of a particular factor or element in a specific situation or context.
Example: "Education plays a significant role when shaping a person's future opportunities."
Alternatives: "an important part when" or "a crucial factor when".
Medium- and long-span bridges of the high-speed rail (HSR) projects play a significant role when crossing certain obstacles, such as rivers, existing highways, etc.
The results show the rock strength plays a significant role when anticipating fracture conductivity, as various formations have behaved differently under different closure stresses.
In most cases a viral infection or a circulatory defect are considered to play a significant role when an alternative satisfactory explanation cannot be found.
The study indicates that although electrostatic forces cause softening characteristics whereas geometric nonlinearity produces stiffening effect on the microstructure, the nonlinearities play a significant role when pull-in occurs.
Given the evident conservation of many structural features between Smc complexes, it is expected that architecture and topology will have a significant role when deciphering their precise molecular mechanisms.
He told the opening day of a US inquiry into the crisis it was big bad Europe that played a significant role when it recklessly bought dodgy US mortgages without checking to see if the promise of a risk free 10% return was too good to be true.
One possible test of this conclusion might be that the endo-glucanases and xylanases as opposed to the exo-glucanases and xylanases, play a more significant role when milling is preceded by a high-temperature ammonia pretreatment than when it is not.
The statute is good for Congress because the legislative branch would get a more significant role when the nation decides whether to go to war.
It has been also found that relative position is playing only a lesser significant role when compared to reduced velocity and size ratio.
This fact may play a more significant role when higher tidal volumes are required, and greater differences in peak pressures between PRVC and VC may be expected.
Both seem to play a much less significant role when compared to WT (e.g. GASA2/GASA3 showed the opposite responses in the two genotypes).
