The phrase "a significant repression of" is correct and usable in written English.
It can be used when discussing the act of suppressing or restraining something to a considerable degree, often in a social, political, or psychological context.
Example: "The government imposed a significant repression of free speech, limiting citizens' ability to express dissenting opinions."
Alternatives: "a considerable suppression of" or "a notable curtailment of".
Treatment of PMC42 cells with BMP7 resulted in a significant repression of the hTERT gene promoter.
In both cell types, SHARP-1 and -2 showed a significant repression of the basal reporter gene activity between 2- and 6-fold and when either BMAL1, NPAS2 or CLOCK expression plasmids were co-transfected (Figure S5B,C).
Thus, in the conditioned compared to non-conditioned animals there was a significant repression of SS 4 splicing (E20 or the respective E21 in NRXN1α) in NRXN1/2/3α (p = 0.002, p = 0.042 and p = 0.002, respectively) in the hippocampus Fig 6 panels A, B and C).
It appears that there is a significant repression of recombination throughout this region.
Our time course experiments did not show a significant repression of Ldlr levels until 24 h further highlighting the complex nature of Srebf2 regulation.
SREBP1: The first 16 h of fasting caused a significant repression of the hepatic expression of SREBP1 (2- and 4-fold for Fst16 and Fst48 states respectively).
Moreover, we observed a highly significant repression of 2-hydroxyphytanoyl-CoA-lyase.
For example, experimental models of diabetes revealed a significant repression [ 48] or no change [ 49] in GLUT1 density and glucose transport at BBB.
On the contrary, cotransfection of β-cateninΔN with AmphiVent2-luc resulted in a modest but significant repression of the reporter gene.
These experiments indicated that most of the selected miRNAs produced a direct effect with significant repression of luciferase activity as compared with the controls (Figure 2).
EZH2α overexpression resulted in the significant repression of a subnetwork of targets that associates to the regulation of cellular growth, cell cycle and proliferation.
