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The phrase "a significant refinement of the" is correct and usable in written English.
It can be used when discussing improvements or enhancements made to a particular concept, process, or product.
Example: "The latest version of the software includes a significant refinement of the user interface, making it more intuitive and user-friendly."
Alternatives: "a notable improvement to the" or "a considerable enhancement of the".
Exact(3)
A significant refinement of the javelin was the Roman pilum.
The addition of Zr to the Mg 2.4Zn 0.1Ag 0.1Ca alloy resulted in a significant refinement of the grain size.
Increasing the solidification rate results only at mould thicknesses of 4 mm and below in a significant refinement of the particle microstructure, necessitating liquid metal deposition techniques to utilise it for obtained improved mechanical performance of HMS.
Similar(57)
A significant refinement of this technê is found in Cicero's On Ends.
The right of union officials to exercise their Fifth Amendment rights was upheld and a significant refinement of constitutional law made when the U.S. Supreme Court reaffirmed the right of union officials to not divulge the location of union records in Curcio v. United States, 354 U.S. 118 (1957).
In addition, an increase in the amount of Zn in the applied alloy gives rise to a significant refinement of magnesium grain size and an improvement in the mechanical properties, such as the compression strength, of the porous MgZn specimens.
An increase of the atomic fraction of Cr induces a significant refinement of grain sizes, from ∼100 nm for a Cu96Cr4 alloy to ∼30 nm in the case of a Cu20Cr80 alloy.
Here, we present a significant refinement of a previously reported technique to integrate QD at the ends of MWCNTs and report a novel MWCNT QD MWCNT heterostructure with detailed chemical and physical characterization of the heterojunctions conducted via Fourier transform infrared spectroscopy, transmission electron microscopy (TEM) and energy dispersive spectroscopy.
The current model represents a significant refinement of our earlier version in terms of model structure, parameter assignment and scenario design [4].
The results indicate that a high degree of superheating for the reverse bainitic α→γ transformation was realized as a result of extremely rapid heating (1000°C/s) up to an elevated austenitisation temperature (1250°C), which prevent restoration of the initial coarse-grained austenite and lead to a significant refinement of austenite grain.
In a significant refinement of methods, we focus on providing public input to institutional practice and governance of biobanks using a tailored workbook structure to guide participants' discussion.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com