The phrase "a significant reason for" is correct and usable in written English.
It can be used when explaining a major factor or cause behind a particular situation or outcome.
Example: "The lack of funding was a significant reason for the project's failure."
Alternatives: "a major factor in" or "a key cause of".
A significant reason for their achievement has been the hiring of coaches from more established soccer-playing countries.
In Hakimpara camp, however, a significant reason for not producing milk is the emotional trauma that comes with displacement.
For the first time, the BJP's vote share across cities and India's vast countryside was similar, a significant reason for the party's success.
But ask yourself: isn't a lack of aspirational female characters in these genres likely to be a significant reason for that?
On the contrary, said Kozul-Wright: "A significant reason for success was not so much their own internal dynamics, as a very favourable set of external growth circumstances".
Also, the use of regulation to keep the banking sector in check denied the central bank a significant reason for raising rates.
The localization of a particular spirit in a specific mask must be considered a highly significant reason for its existence.
For J. S. Mill, this is a very significant reason for open ballots.
In The Netherlands, for example, pain has been found to be a less significant reason for requesting assistance with dying than other forms of suffering, including frustration over loss of independence.
The next day, however, Skilling admitted that a very significant reason for his departure was Enron's faltering price in the stock market.
A second significant reason for focusing on the X arose from the costs related to obtaining very high levels of sequence coverage necessary for the study of recombination on autosomes.
