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A significant ramification of the above is that the most important interactions between clinically relevant quinolones and their enzyme targets are mediated through the C3/C4 keto acid of the drug skeleton.
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Instead, a bill with significant ramifications for criminal law and immigration cases was introduced just last week, while members were out of town, and is being rushed to the floor today without any adequate opportunity for review by the public, by legal experts, or by stakeholders". Republicans defended the quick vote.
Every 15 minutes that a stroke goes untreated means significant ramifications for a patient.
For researchers and clinical trialists, the issue of sensitivity to change for a particular instrument has significant ramifications for whether or not a meaningful treatment effect will be detected between placebo and treatment groups.
The Premiership club have made their first steps towards a major relocation that could have significant ramifications for a number of other teams and Coventry City Football Club, with members of Coventry city council unanimously voting in favour of their Ricoh purchase on Tuesday evening.
It may be sobering for leaders to realize that, with a given promotion or a new hire, theyre making a decision that could have significant ramifications for the company for five or 10 years, or even longer.
The AWC asserts that Non-Traditional ETFs generally "reset" daily, and such a factor can have significant ramifications that distort the performance of the subject ETF and its underlying index or benchmark.
Understanding the molecular-level mechanisms that enzymes employ to deconstruct plant cell walls is a fundamental scientific challenge with significant ramifications for renewable fuel production from biomass.
This institution cannot stand by idly as a war of choice with significant ramifications for our national and economic security is waged without Congress fulfilling its responsibilities under the constitution.
Koh stressed he retains confidence in the project saying a folding Galaxy 'would have significant ramifications' for the entire industry.
This difference in emphasis on the part of the rationalist can have significant ramifications for a generalized 2D semantics.
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CEO of Professional Science Editing for Scientists @ prosciediting.com