Study design characteristics accounted for a significant proportion of between-study heterogeneity, and there was evidence of a significant publication bias.
Comorbidity accounted for a significant proportion of between-study heterogeneity for survival (χ=40.1, df=3; P<0.0043, Figure 3A), with efficacy being significantly greater in animals with comorbidities, but not for tumour volume.
Delay to treatment was stratified into groups of 0, 11 20 11–20 and >20 days post-inoculation, and this accounted for a significant proportion of between-study heterogeneity for both MSR and volume reduction (MSR: χ=47.0, df=4; P<0.0043; volume: χ=45.9, df=3; P<0.0039).
Eunicella cavolinii explained a significant proportion of differences between the seamount flanks, but only at 80 90 m (19%) and at 90 100 m (27%).
The communalities point out a significant proportion of variance (between 41% and 80%) of original variables explained by the complete set of derived factors.
Drawbacks of this study included the recruitment of a significant proportion of patients between the age of 65 and 70, and the fact that capecitabine proved to be a rather toxic control arm.
Finally, we found little evidence that any of the country-level variables explained a significant proportion of heterogeneity between countries in the effects of living arrangement on the predicted prevalence of depressive symptoms.
Several studies suggest that a significant proportion of patients (between 30 50%) will respond poorly to antidepressants and may develop a chronic, cycling course of illness with more frequent depressive episodes, more suicidal behaviour and, in the longer-term, more treatment-resistance [ 8, 9].
Actually, the majority of Tourette's patients don't have coprolalia, although a significant proportion do, estimated at between 25 per and 50 per cent.
