Sentence examples for a significant problem due to from inspiring English sources

Unlike this larger gecko, the Virgin Islands dwarf sphaero lives on drier hillsides, yet prefers moist microhabitats found under rocks because it lacks the adaptations necessary for preventing water loss, which is a significant problem due to its small body size.

However, resistance to antitubulin drugs has become a significant problem due to P-glycoprotein overexpression and, perhaps, to mutations in genes encoding the tubulin subunits, changes in tubulin isotype composition of MTs, altered expression or binding of MT-regulatory proteins including Tau, mutations in or reduced levels of γ-actin, and/or a reduced apoptotic response [3], [6].

Transport of temperature sensitive reagents needed for diagnostic procedures was also a significant problem due to unavailability of commercial "dry-ice" refrigerated transport service in Sierra Leone.

Access to medicines in developing countries continues to be a significant problem due to lack of insurance and lack of affordability.

Antimonial resistance has been reported [ 16– 19] and it should be considered a significant problem due to the limited drug arsenal for treatment of this disease [ 20].

Even though mortality from rotavirus infection is no longer a significant problem due to easy access to medical care in Taiwan, the morbidity due to rotavirus is still very high.

However, the relatively poorer performance of the greedy methods in shadowed concave regions now becomes a more significant problem due to the prevalence of concave regions such as creases on the clothes.

Natural convection in an enclosure (internal convection) is an important problem due to its significant practical applications.

When speech recognition is to be used in arbitrary, noisy environments, interfering speech poses significant problems due to the ovelapping spectra and nonstationarity.

Furthermore, Sarkar et al. argue that treatment for HCV is warranted for patients without extensive liver damage if they are experiencing significant problems due to fatigue [ 7].

Migraine is a neurologic disorder that represents a significant health problem due to the frequency and accompanying morbidity that includes disability and loss of performance [1 3].