This 7.7 kb window becomes most significant just at the point when it encapsulates the 900 bp window at its downstream edge.
A significant point that arose when analyzing animal RBR genes was the correlation found between their evolutionary conservation and their patterns of expression.
December 2008 marked a significant point in the history of the Guardian when the paper moved to a brand new building in King's Cross after 32 years in its Farringdon headquarters.
A significant points grab came when he finished second in the 110m hurdles among the 25 competitors still in the hunt, down from the 32 who started, with a time of 13.58sec.
But the Heat may have taken a significant hit when its starting point guard, Mario Chalmers, was carried off the floor late in the first quarter with what was preliminarily diagnosed as a sprained right knee.
"I think the significant point was when he came out and said he was in it for the long haul, he wanted to do the job," said the restored national coach.
The significant point is when the oversold condition is over and the market is turning back toward the next overbought reading.
And having a high blood-sugar level may reach a tipping point – or a point when small changes become significant enough to cause a big change – and you develop diabetes.
The threshold indicating allograft damage by current post-transplant biomarkers is high and reached at a point when significant damage has already occurred.
But the possibility of disruption in this normal pattern becomes a significant issue at reception point when the choice path contains the options 'mediated: congruent', as it does for P; this is because mediation always leads to the text's 'displacement' from its point of production, and this normally involves the intervention of a mechanical and/or human agency other than the speaker.
As Gilbert points out, this glitch is also significant when it comes to negative events like losing a job or the death of someone we love, in response to which we project a permanently inconsolable future.
