The phrase "a significant overall decline" is correct and usable in written English.
It can be used when discussing a noticeable decrease in a particular area, such as performance, sales, or health metrics.
Example: "The report indicated a significant overall decline in customer satisfaction over the past year."
Alternatives: "a marked overall decrease" or "a considerable overall drop."
Nick Hardwick, in his last report, says that staff shortages, overcrowding and a rising level of violence fuelled by a rapid increase in the use of legal highs have all contributed to a significant overall decline in safety.
Even if we could find a significant overall decline in bone turnover markers, only 52/77 patients had a decrease in bone turnover markers, while 25 had not.
Although there was a significant overall decline in interest (χ=15.13, P=0.000, McNemar test), there was no significant difference between risk groups at baseline (χ(10)=6.15, P=0.80) or follow-up (χ(10)=4.93, P=0.90).
Although we observed a significant overall decline in NP-specific CD8+ T-cell avidity over time, it remains unclear whether this relates to a specific loss of polyfunctional CD8+ T cells.
There was a significant overall decline in eGFR over 6 years in the entire cohort as calculated by CKD-EPI creatinine (P < 0.0001), cystatin C (P < 0.0001), and combined creatinine and cystatin C (P < 0.0001).
In Malawi, two broad geographic trends emerge of HIV/AIDS prevalence among pregnant women attending ANCs: 1) a significant overall decline in prevalence since the peak of the epidemic in 1999, and 2) multiple geographically defined HIV 'epidemics' with diverse spatiotemporal trends.
Because reduction in ambulatory activities that might result from hip and knee OA can have other health impacts, poor pain control is likely to result in a significant overall functional decline.
Two studies in HGG patients assessing HRQoL preoperatively and 6 weeks after surgery revealed a slight, non-significant, overall decline in median HRQoL scores at the group level [30], [31].
Control group The one-way repeated-measures ANOVA showed a significant overall time-dependent decline in pain perceived in the placebo side (P < 0.0001).
In both study series, a significant overall trend of declining caries experience and level of untreated caries, and an increasing trend of percentage of caries-free children was observed (p < 0.05).
In the HHR group, despite a slight decline in physical symptoms after 6 months, there was a significant overall improvement from the pre-operative level.
