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The phrase "a significant negative" is correct and usable in written English.
It can be used in contexts where you are discussing a notable or considerable negative aspect, outcome, or impact of something.
Example: "The study revealed a significant negative correlation between stress levels and academic performance."
Alternatives: "a considerable drawback" or "a major disadvantage".
Exact(60)
"This could have a significant negative impact".
Sulgrove as West now had a significant negative clue.
NH4NO3 has a significant negative effect.
Still, a significant negative reaction could easily arise.
Conversely, corporate misdeeds, once they become known, do have a significant negative impact on financial performance.
We observed a significant negative correlation between leukocytosis and hypokalemia.
Job satisfaction had a significant negative impact on turnover intentions.
Trees generally had a significant negative effect on maize yield.
ADHD may have a significant negative impact on academic performance.
Concerns about hierarchy may have a significant negative impact on hand hygiene advocacy.
A significant negative linear relationship was found after log transformation (p = 0.014, R2 = 0.381).
More suggestions(18)
a noteworthy negative
a considerable negative
a vital negative
a prominent negative
a substantial negative
a significant disadvantageous
a notable negative
a significant downward
a significant unfavorable
a tangible negative
a large negative
a major negative
a significant undesirable
a significant passive
a significant damaging
a significant prejudicial
a huge negative
a tremendous negative
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com