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The population showed a significant modulation in firing rate in response to USVs.
Finally, a significant modulation in expression of genes related to cellular proliferation and differentiation was observed.
Enrichment analysis revealed a significant modulation in Epithelial to Mesenchymal Transition (EMT), apoptosis and TGFbeta signaling pathways.
Furthermore, we did not observe a significant modulation in the absolute number of peripheral MDSCs (data not shown) with respect to the untreated tumor-bearing mice.
In particular, 31 out of 54 neurons (57%) showed a significant modulation in MOV, and 31 out of 54 (57%) in HOLD (anova, P < 0.05).
Of note, in RA SM and T cell co-cultures, adding CTLA-4-Ig at a lower concentration (100 μg/ml) induced a significant modulation in TNFα expression alone (P < 0.001; Figures 6c and 6d).
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Regarding the ADM muscle, we did not detect any significant modulation in RHD patients (P > 0.1).
We did not observe any significant modulation in Foxp3 expression between moAb-Il6r-treated and untreated mdx mice (Fig. 3F).
We failed to observe any significant modulation in the levels of total and phosphorylated forms of proteins involved in JAK/STAT signalling such as JAK2, STAT5, STAT3, as well as Akt and 4eBP1, GATA-1, Pim1 and Bcl-xL.
Again, average firing rates did not show any significant modulation in relation to baseline throughout the whole period of training (DS: F8,160 = 1.031, p = 0.4153; M1: F8,384 = 1.757, p = 0.084; Figure 4J).
Importantly, while we did not observe a significant modulation difference in the OFC to amygdala connection, the sum of the posterior intrinsic connectivity parameters and modulation parameters in SAD patients yields a net modulation that is not significantly different from zero (Fig. 5).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com