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The phrase "a significant marker of" is correct and usable in written English.
It can be used to indicate that something serves as an important indicator or symbol of a particular quality, condition, or phenomenon.
Example: "The increase in temperature is a significant marker of climate change."
Alternatives: "an important indicator of" or "a key sign of".
Exact(30)
The mention of the job market is a significant marker of Mr. Powell's views.
The movie will stand up as a significant marker of the crushing American dilemma of overconsumption and underproduction.
On Sunday she will play for England against Germany in a significant marker of how much women's football has developed.
That change is a significant marker of shifting attitudes in the history of the city's homeless policy.
"This is a significant marker of a deteriorating relationship," said State Senator Bill Perkins, who organized a march on Thursday to protest the doll's head.
Heart rate variability (HRV) is a significant marker of health outcomes with decreased HRV predicting increased disease risk.
Similar(30)
Moreover, ΔT was a significant marker for the discrimination of the type of malignant or benign lesion.
(The presence of a stepfather is a significant marker for the sexual abuse of girls. But Daly and Wilson's theory makes no prediction about this, and it's a well-known phenomenon).
By Adam Gopnik March 21, 2017 Ivanka Trump attended the Broadway musical "Come from Away" alongside Justin Trudeau, a reminder that popular culture is a less significant marker of public attitudes than its close readers would wish.
Dr Ray Macdonald, an expert in the psychology of music at Glasgow Caledonian University, says that this scheme plays on the fact that "music is a very significant marker of identity in young people and defines who they are... so they will disassociate from music they don't like".
MTV Base Africa, as it is formally known, is a modest but significant marker of the many changes and a new kind of hope that capitalism and technology are bringing to a land of heartbreak and broken economies.
More suggestions(16)
a momentous marker of
a substantial marker of
a tangible marker of
a huge marker of
a significant milestone of
a significant score of
a remarkable marker of
a notable marker of
a prominent marker of
a significant gauge of
a significant symbol of
a significant percentage of
a significant part of
a significant chunk of
a significant amount of
a significant aspect of
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com