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Either way, though, it has laid down a significant marker.
Bonds is only 7 home runs from 700, which is a significant marker but not a record breaker.
The movie will stand up as a significant marker of the crushing American dilemma of overconsumption and underproduction.
On Sunday she will play for England against Germany in a significant marker of how much women's football has developed.
That change is a significant marker of shifting attitudes in the history of the city's homeless policy.
But winning the popular vote in Pennsylvania would be a significant marker.
"This is a significant marker of a deteriorating relationship," said State Senator Bill Perkins, who organized a march on Thursday to protest the doll's head.
For Basil Hero, the release of "Death of a Salesman" is a significant marker in his quest to find Broadway productions that were adapted for television and to restore the aging films and tapes using digital technology.
Studies that assess a large number of the risk factors for violent abuse or neglect — as a study at Columbia University did in 1998 — consistently find that the presence of a stepfather isn't a significant marker of risk.
(The presence of a stepfather is a significant marker for the sexual abuse of girls. But Daly and Wilson's theory makes no prediction about this, and it's a well-known phenomenon).
In Hampton's first and only other outing this year against the Mets, May 10 in Denver, he pitched a shutout, a 6-0 vintory in Coors Field that seemed a significant marker for each club at the time.
More suggestions(18)
a notable marker
a major marker
a significant landmark
a significant gauge
a prominent marker
a remarkable marker
a noticeable marker
a significant label
a significant score
a substantial marker
a significant symbol
a vital marker
a huge marker
a momentous marker
a significant trace
a significant beacon
a significant milestone
a significant indicator
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com