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"It's a significant issue".
And the cost is a significant issue.
"But it still is a significant issue.
This is a significant issue to people.
"It's a significant issue, and I think it's a significant issue of public concern," Blair said.
Medication safety is a significant issue.
Academics have been a significant issue, especially math, administrators say.
Control of the police is a significant issue.
"Unintentional collection is not viewed as a significant issue".
Falling participation figures have been a significant issue for golf.
Jeremy wasn't a significant issue at this election".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com