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In some cases lack of information extended to the procedure and outcomes, and this was occasionally a significant issue: " I wasn't told that it might not work, and definitely no mention that my symptoms could get worse.
While access was not mentioned as a primary barrier to use in the DHS data used in our analysis, it may still be a significant issue.
"The court's decision to preclude all mention of the risks of other diet drugs in this case will be a significant issue on appeal," Mr. Sims said.
"It's a significant issue".
And the cost is a significant issue.
"But it still is a significant issue.
This is a significant issue to people.
Academics have been a significant issue, especially math, administrators say.
Control of the police is a significant issue.
"Unintentional collection is not viewed as a significant issue".
Falling participation figures have been a significant issue for golf.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com