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The phrase "a significant hit" is correct and usable in written English.
It can be used to describe something that has had a considerable impact or success, often in the context of sales, popularity, or effectiveness.
Example: "The new movie was a significant hit at the box office, breaking several records in its opening weekend."
Alternatives: "a major success" or "a considerable success."
Exact(60)
The governor called the development "a significant hit to the New York economy".
This, in itself, would amount to a significant hit to creditors.
From that point to this, however, Falcao's career has taken a significant hit.
A television commercial featured a rap group that last had a significant hit 25 years ago.
That would deliver a significant hit to the economy next year.
As a result his credibility took a significant hit, and in recent weeks he was increasingly accused of perjury.
The news for cinemas continues to improve with the arrival on 27 March of Cinderella – already a significant hit in other territories.
On RTÉ radio's Morning Ireland, Ajai Chopra, the head of the IMF mission to Ireland, left the door open to senior bondholders taking a significant hit.
"I guarantee you," Mr. Berkley said, "as we move down the line, the profits you're seeing in the business today are going to take a significant hit.
They are now subject to European banking regulations that would force the bank's bondholders to take a significant hit before the state can inject funds.
His talent was such that the average listener noticed it right away, and he had a significant hit with his first single, "Moonlight in Vermont" (1952).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com