Drug addiction, a leading health problem, is a chronic brain disease with a significant genetic component.
The tendency for familial aggregation and the findings of gene variation association studies implicate a significant genetic component in the development of AMD.
There is persisting interest in the idea that taste preferences are heritable characteristics, but few twin studies have found evidence for a significant genetic component.
We hypothesize that aging and longevity, as complex traits having a significant genetic component, are likely to be controlled by nuclear gene variants interacting with both inherited and somatic mtDNA variability.
Schizophrenia (SCZ) and bipolar disorder (BPD) are major psychotic disorders with a significant genetic component in their complex etiology [6].
Existing studies indicate a significant genetic component for sudden cardiac arrest (SCA) and genome-wide association studies (GWAS) provide an unbiased approach for identification of novel genes.
The increased risk in specific breeds suggests a significant genetic component, influencing the power of mapping the genetic risk factors underlying SLO.
Dropping C from the model resulted in a worse fitting model (p = 0.035 for chi-square change; Δχ2 = 4.430, Δdf = 1); in the resulting AE model a significant genetic component could be observed.
In summary, the neurobiology of cognitive aging suggests that several factors contribute to the level of cognitive ability in aged individuals, including a significant genetic component and a critical role of environmental and social factors.
Despite considerable evidence that the deficit in intellectual function in DMD has a significant genetic component a simple relationship between the degree of cognitive impairment and the severity of muscle weakness has not been identified, suggesting that these interrelated phenotypes are under a degree of tissue specific control.
However, cardiovascular disease also has a significant genetic component.
