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The phrase "a significant framework for" is correct and usable in written English.
It can be used when discussing a foundational structure or system that supports or guides a particular concept, idea, or process.
Example: "The research provides a significant framework for understanding the complexities of climate change."
Alternatives: "an important basis for" or "a crucial structure for".
Exact(2)
A very low root mean square deviation (0.82 Å) from template structure and stereochemical quality of constructed BmGST model proposed it as a significant framework for further analysis.
This is a significant framework for health for people's health involving all sectors and for the health sector itself with more than 30 explicit references to health, which refer to implementation of an all-hazards approaches (Kelman 2015) and link to epidemics and pandemics in addition to the 2005 International Health Regulations (WHO 2005).
Similar(58)
The down-regulation of MMP-2, MMP-3, MMP-9, p53 and VEGF in DSPP-silenced OSC2 cells provides a significant functional/molecular framework for deciphering the mechanisms of DSPP activities in oral cancer biology.
Since in the scientific and technical literature multiple, sometimes incompatible, definitions of 'measurement' can be found, identifying a single conceptual framework is a significant target for measurement science, towards a generalized concept of measurement, in compliance with the notion of widely-defined measurement proposed by Ludwik Finkelstein.
In order to deal with such challenges in a systematic way, there is a significant need for an information technology framework together with related analytical and computational tools that will facilitate integration of models and simulations of complex biological systems.
Such a reference model is an abstract framework for understanding significant entities and relationships between them within a service-oriented environment [8] such as a service-oriented data infrastructure.
But when it's something that's significant, we have a framework for discussing it and respecting each other's feelings".
A reference model is an abstract framework for understanding significant entities and relationships between them and thus helps to understand existing data infrastructures when comparing them in terms of functionality, services, and boundary conditions.
It is not surprising that comparing the contact details between NIH-CPSI and IIEF-5 within the greater population has a highly significant and might provide a framework for understanding of the association between ED and CP/CPPS in China.
Additionally, sequenced RAD markers arrayed in genetic maps would be of significant benefit as a scaffold framework for placement of shotgun sequence reads and de novo genome assembly refinement.
The Senate voted, 51 to 45, largely along party lines, to endorse a Republican-written budget blueprint that is nonbinding but is politically significant because it provides a framework for specific spending and tax bills for the fiscal year 2001, which begins Oct. 1.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com