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In our review, 13 of 187 children were found to have a significant fracture.
Extrapolation of our results (13/187) suggests that approximately 13 of the remaining 181 children (who had negative radiographs) would have had a significant fracture.
In a multicenter study in North America that used the same definition of ankle fractures as we did, 45 of 226 children with AAI and high clinical suspicion of fracture were found to have a significant fracture following routine plain radiographs (Boutis et al. 2001).
Mary found that she was in a position where she had to advocate on behalf of her mother when the hospital system seemed to be a little slow in working towards encouraging the mobility of her mother following a significant fracture: I was trying to push everybody to get her on her feet, get her back to the care home, given they weren't going to operate or anything.
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The risk reductions were attenuated in both trials post intervention; however, a significant hip fracture benefit persisted over 13 years for women assigned to the combination therapy.
Dan Tuohy will have exploratory surgery on a "significant" ankle fracture before a date is determined for his return.
The results of the WHI study showed a significant reduction in all fractures in a population of patients who likely did not have significant fracture risk, based on the Body Mass Index (BMI), age and BMD results within the sub-group [ 5, 12].
It is a disorder associated with significant fracture-related morbidity in elderly postmenopausal women, including negative effects on quality of life because of chronic pain, depression, and limitations on social activity, 4– 7 as well as increased mortality.
This was in an old mine, where significant fracturing of the rock was evident, resulting in substantially more localized rock deformation than was initially predicted.
That approach, however, has been suggested to be over-treatment, with a very low rate of significant fractures at the cost of significant time lost from work or school [5 7].
However, we did not observe a significant difference in fracture risk, when pathologic fractures and SCC were excluded.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com