Sentence examples for a significant exacerbation from inspiring English sources

Hammar et al. [ 13] investigated 124 patients before and after treatment with GnRH analogs and concluded that there was a significant exacerbation of gastrointestinal symptoms after treatment, and abdominal pain was still exacerbated at 5-year follow-up.

They also exhibited a significant exacerbation of the normal gap/overlap effect, consistent with 'sticky fixation'.

For people with persisting symptoms, a significant exacerbation in positive symptoms was required, typically leading to hospital admission.

In mice with allergic airway inflammation, dsRNA challenges caused a significant exacerbation increasing lung tissue inflammation score and tissue neutrophilia.

In contrast, glatiramer acetate treatment in BDNFind−/− mice was significantly less effective and mice displayed a significant exacerbation of the disease in the late phase (Fig.  5a).

A number of AEDs, including carbamazepine, phenytoin and vigabatrin should be avoided in MAE because they frequently result in a significant exacerbation of seizures [ 11].

However, mCPP did not produce any significant exacerbation of obsessive compulsive symptoms in the patient group.

A selection bias may have been inadvertently created for patients well enough to participate or more motivated to participate in trials, or who had not had any significant exacerbations of medical conditions that would prevent inclusion in a clinical trial.

There was a small but statistically significant exacerbation of lavage fluid protein 24 hours after LPS in animals exposed to 100 ppm CO, consistent with a recent study showing that 50 ppm CO alone induced small increases in protein levels in lavage fluid of rats [33].

A significant temporary exacerbation in the glycaemic control was found after the Great Hanshin-Awaji Earthquake.

However, ≥100 µg/animal of MOG-specific monoclonal antibody is normally required to obtain a significant acute exacerbation of disease severity and/or pathology in experimental autoimmune encephalomyelitis (Linington et al., 1988; Mathey et al., 2007).