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The phrase "a significant escalation of" is correct and usable in written English.
You can use it when discussing an increase in intensity, severity, or magnitude of a situation or issue.
Example: "The report indicates a significant escalation of tensions between the two countries over trade disputes."
Alternatives: "a considerable increase in" or "a major rise in".
Exact(60)
So waiving it, even temporarily, is a significant escalation of the Fed's rescue efforts.
Gracie's resignation has caused a significant escalation of the pay row at the BBC.
This appears to be the first sign of a significant escalation of activity in the inquiry.
The bank's vigorous response Sunday was a significant escalation of the milder intervention of the past.
The Obama administration continues to hold out for a significant escalation of European resources in the region.
The announcement this month was viewed as a significant escalation of the risks Silicon Valley faces with regulators.
However, North Korea's actions against Sony are considered by many a "game changer" and a significant escalation of the cyber hostilities targeting corporations.
The game, the first in the regular season to be played outside North America, represents a significant escalation of Major League Baseball's international aspirations.
The suit marks a significant escalation of the legal campaign that has been waged against the industry by 32 cities and counties around the country.
Tory MPs welcomed the decision, which marks a significant escalation of the policy Cameron has adopted of allowing honours to be awarded for political service.
People's Liberation Army Navy ships challenged three Australian warships sailing through the sea last month, in a significant escalation of Chinese assertiveness in the region.
More suggestions(16)
a significant aggravation of
a remarkable escalation of
a significant intensification of
a huge escalation of
a substantial escalation of
a significant exacerbation of
a significant recrudescence of
a significant deterioration of
a significant amplification of
a significant worsening of
a significant build up of
a significant stepping up of
a significant percentage of
a significant part of
a recent escalation of
a sharp escalation of
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com