The phrase "a significant enlargement" is correct and usable in written English.
It can be used when discussing an increase in size, scope, or extent, often in contexts such as business, research, or physical dimensions.
Example: "The recent study revealed a significant enlargement of the tumor, indicating a need for immediate medical intervention."
Alternatives: "a considerable increase" or "a substantial expansion."
Expression of Val12-Ha-Ras results in a significant enlargement of pyramidal neurons.
This principle facilitates the statistical evaluation of haplotype matches due to a significant enlargement of sample sizes.
Ligation of the left common carotid artery in 6-month-old wild-type (C57 black/6J) mice for 4 weeks induced a concentric remodeling with vessel wall thickening, characterized by cell proliferation in neointima, media, and adventitia, and with lumen narrowing without a significant enlargement of overall vessel dimension.
A significant enlargement of the IMA on the malignant side occurs in most patients.
Assessing the stability of the HPP, one question has always been whether ongoing karstification could lead to a significant enlargement of the karst cavities.
In the presence of malignancy this study showed a significant enlargement in the cross-sectional area of the IMA and IMV on the malignant side.
Area measurements suggest a modest but significant enlargement of the caudal striatum in KO animals as compared to controls (Fig. 4B).
The single cell at the tip undergoes two successive divisions without significant enlargement, leading to a 4-cell head of around 25 30 μm diameter (Fig. 3c, i, o and u).
In animals receiving aminoacetonitrile, a less toxic analog of BAPN, electron microscopy of long bones shows significant enlargement of Type I collagen fibrils while a similar but less severe abnormality is observed in vitamin B6-deficiency and in hyperhomocysteinemia induced by hCySH added to the diet [ 13].
We hypothesized that submandibular gland resection could offer a significant cranial enlargement of the operative field, up to the clivus.
When quantifying the area of the different cavities we found a significant (p<0.01) enlargement in relation to actual implant size made by tethered implants regardless of diameter (Figure 5E).
