The phrase "a significant effort in" is correct and can be used in written English.
For example, "The company has put in a significant effort in creating a sustainable, long-term business model."
"Republicans are obviously going to invest a significant effort in trying to peel away white Democrats from the Democratic candidate".
Meanwhile, malware authors expended a significant effort in developing new ransomware that improved evasion techniques and spreading abilities.
Confronted with the skepticism of Quine, his student Donald Davidson made a significant effort in the 1960s and '70s to resuscitate meaning.
Sam Mendes made a significant effort in Skyfall to redesign the Bond film as prestige cinema; in his second outing he's at equally dedicated pains to reset the status quo.
Dark Energy Probes: We have a significant effort in (weak) gravitational lensing and a portion of the group works on the supernova cosmology project, and potential Dark Energy satellite probes such as EUCLID or JDEM.
In April, a top Sanders advisor told the Guardian that the Vermont senator would put together "a real campaign that will raise significant resources" which relied on low-dollar donors online and would provide enough to fully fund a significant effort in the early primary states.
It has only half the dimension of PROSPECT features (see Section 6.1.3), hence leading to a significant effort reduction in the likelihood calculation of the BGs and showing better accuracy than MFCC.
The work of the Akuka mothers' club is a highly significant effort in a country where some 74,000 children under the age of five continue to die from preventable causes every year.
"We make a significant effort to engage in Twitter and Facebook around administration priorities," Howard Wolfson, a deputy mayor, said.
The United States has made a significant effort and investment in STEM education, yet the size and the composition of the STEM workforce continues to fail to meet demand.
In order to bolster the pipeline a significant effort has been applied in repurposing drugs from different indications.
