The phrase "a significant effort by" is correct and usable in written English.
It can be used to describe the considerable work or contribution made by someone or a group towards a particular goal or project.
Example: "The success of the initiative was largely due to a significant effort by the volunteers who dedicated their time and resources."
Alternatives: "a considerable contribution from" or "a substantial effort from".
The documents show a significant effort by the company to enhance its reputation, including hiring a consultant, KPMG, to advise it on a corporate responsibility program.
Pursuing this type of approach will take a significant effort by both technologists and political experts in order to design plausible solutions.
In the last two decades I've witnessed a significant effort by many young physicians to push back against those career pressures, as they seek more balance in their lives.
The release in late 2011 of the first volume of the new magazine, called Pathlight: New Chinese Writing and overseen by the editor in chief of Renmin wenxue, marked a significant effort by one of China's most prestigious publications to raise worldwide awareness of contemporary Chinese writing.
We are still awaiting a significant effort by the "disrupted" parties to deal with this challenge, but Comcast and Netflix may soon embrace the convergence.
While there is a significant effort by environmentalists to get oil companies to make low-sulfur fuel available, high costs have been a stumbling block.
These reductions represent a significant effort of successful nutrient conservation by the farms in the study.
But any larger US air action might have to be preceded by a significant effort to destroy missiles, associated radars and command systems and might well involve losses.
Axelrod added that the Obama administration has made a significant effort to add safeguards, headed by briefings of Congress.
EuPathDB has invested a significant effort in ensuring data integration by mapping metadata to already established ontologies such as the Ontology of Biomedical Investigation (see accompanying manuscript describing data management of ICEMR projects).
However, the establishment of a uniform specification will require significant effort by the journals and the scientific resource projects.
