The phrase "a significant distinction between" is correct and usable in written English.
It can be used when discussing differences or contrasts between two or more subjects, highlighting the importance of those differences.
Example: "There is a significant distinction between qualitative and quantitative research methods that researchers must understand."
Alternatives: "a notable difference between" or "a key contrast between".
This detail illuminates a significant distinction between "Lady Bird" and a wide range of notable independent films.
Furthermore, the empirical evidence suggests the need for introducing a significant distinction between instrumental-expert and expressive mobilization.
A significant distinction between the London cab and its American counterpart is the use of a diesel power plant.
Katina Zachmanoglou New York, Jan . 31 , 2008 To the Editor: Re "The Dynastic Question," by Nicholas D. Kristof (column, Jan. 31): Mr. Kristof did not make a significant distinction between the Bush family and the Clinton family.
A significant distinction between the existing approaches to ADR prediction is whether the predictions are generated for drug-like molecules currently in development, or for drugs that have undergone clinical trials.
And he said there is a significant distinction between people like Mr. Hudson and Mr. Sinatra who are born with famous names, and others who adopt their names later in life.
Second, after removing the main source of variation, unsupervised analysis of gene expression profiles showed a highly significant distinction between two groups, one including positive controls and a sub set of commercial samples, the other comprising all negative controls and the remaining unknown individuals.
It seems problematic to think that a significant distinction can be drawn between first and second-generation rights on the ground that the former, but not the latter, simply require that government refrain from interfering with the actions of persons.
RALYL-IHC analysis revealed a significant distinction in RALYL staining between patient samples (Fig. 6a).
Results from CFA supported the two-factor structure over the one-factor structure of the RPQ, and showed that a significant distinction can be made between reactive aggression and proactive aggression in detained adolescent males.
The prevailing opinion fails to articulate what I deem to be a constitutionally significant distinction between two kinds of governmental bodies.
