The phrase "a significant difference but" is correct and usable in written English.
It can be used when introducing a contrast or exception after stating that there is a notable difference between two or more things.
Example: "There is a significant difference but it does not affect the overall outcome of the experiment."
Alternatives: "a notable difference yet" or "a considerable difference however".
In the present study, comparison of mean age of tumor diagnosis between affected carriers with different MDM2 SNP309 genotypes revealed a significant difference, but the genotype did not significantly affect the hazard for cancer development among all carriers.
It could be argued that the size of the patient sample or that of the different groups was insufficient to detect a significant difference, but the allelic frequency between patients and controls were remarkably similar (Table 1).
I'm proud that we've been able to make such a significant difference, but we are just a stop gap".
"It's a significant difference but I would hesitate to assume all of the normal rules apply this year," he said.
"It is a significant difference, but we should be a bit cautious since it is the first study showing that the risk of cancer of the blood is lower in vegetarians.
All this will make a significant difference, but only if the retailer also deals with pricing compliance across its stores.
That's a significant difference, and but for sixty-seven thousand government jobs that were eliminated, it would have been even bigger.
These analyses had a significant difference before, but not after, Bonferroni correction.
The cues didn't make a significant difference between behaviors, but we were surprised that such a technologically enlightened group didn't take measures to protect people's privacy more.
At 12 months, the activity declined, but the trend for a greater activity was maintained in the treatments with 1 % LRC additions, without a significant difference between them, but with a significant difference from the controls (Table 5).
Colorfastness to light was enhanced with a PAS mordant for black walnut and eastern redcedar, while Osage orange had a significant difference from laundering but not for light.
