The phrase "a significant decrease in the ability" is correct and usable in written English.
It can be used when discussing a reduction in someone's or something's capacity or capability in a specific context.
Example: "The recent changes in policy have led to a significant decrease in the ability of employees to work remotely."
Alternatives: "a notable reduction in the capacity" or "a considerable decline in the capability."
Flow cytometry and WinList™ Interative N-Color Compensation software revealed a significant decrease in the ability of coelomocytes to kill targets following in vitro DMBA exposure, compared to untreated controls where coelomocytes were cultured in the same medium in the absence of DMBA.
In the mutants that showed a significant decrease in the ability to adhere to HCT-8 cells, the Tail PCR method was used to identify the transposon insertion sites (Du et al. 2012).
These results indicate that expression of FGFR4-WT, or of the activated mutant FGFR4-K645E, results in a significant decrease in the ability of TNFα to stimulate NFκB nuclear localization.
We show here that substitution of Q169 in the context of hTERT 1 300 causes a significant decrease in the ability of this fragment to bind ssDNA primers comprised of random or yeast telomeric ssDNA (Figure 6B).
Taken together, the results of our study suggest that PC is characterized by a significant decrease in the ability of the immune system to respond to non-self antigens, including tumor associated antigens, as summarized in Figure 3.
Moreover, a significant decrease in the ability of the cells to resume growth was noticed.
Silencing of the ZmPti1a gene resulted in a significant decrease in the competitive ability of pollen.
Experimental data showed a significant decrease in the clonogenic ability of treated tumor cells as compared with the negative control.
siRNA-mediated silencing of MIF resulted in a significant decrease in the invasive ability of the cells (p-value <0.05) (Fig. 4a).
At early time points (10 h) we observed a significant decrease in the migration ability of E-cadh and P-cadh-positive cells compared to control cells.
Our results show a significant decrease in the sensorimotor abilities that can be easy quantified using objective kinematic and kinetic parameters.
