After 24 72 h exposure, all treated groups showed a significant decrease in cell viability.
There was also a significant decrease in cell capacitance.
Treatment with ibrutinib (1 μM) resulted in a significant decrease in CLL cell viability in non-del 8p) non-del 8pP=0.02; one-sided paired t-test) and to a lesser extent in del(8p) samples (P=0.06i).
We confirmed that rats infused with oleate for 48 h had a significant decrease in β-cell function.
Lipid infusion resulted in a significant decrease in β-cell function as expected in both rats (p < 0.05) and mice (p < 0.001).
The heavy users of ecstasy, or MDMA, showed a significant decrease in brain cells responsible for reabsorbing serotonin, a messenger chemical involved in mood, appetite, pain perception, sexual drive and memory.
If the cell was successfully recharged to 4.2 V but exhibited a significant decrease in OCV, then the cell was considered to have ISCr, and its OCV was further investigated.
(A) xCELLigence assay showed no significant decrease in cell index for primary human corneal stromal fibroblasts (pHCSFs) treated with 100 500 nM ITF2357, and a graded reduction in cultures treated with 1000 5000 nM ITF2357 for 48 hr (n = 6).
Flow cytometric analysis of mature blood cells showed a significant decrease in the frequency of myeloid cells (CD11b+), granulocytes (Gr-1+) (Fig. 2f,g), whereas the percentage of NK cells (NK1.1+) was not significantly changed (Fig. 2h), 16 weeks after transplantation.
Examination of the CBX6-OE U251MG cells and its control revealed that overexpression of CBX6 also caused a significant decrease in BST2 in U251MG cells (Fig. 7B).
