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We observed a significant decrease in cell surface CLIP on B cells.
Changes in integrin cell surface expression corresponded with the previously observed decreases in gene expression with a significant decrease in cell surface α5 and β1 expression in both MDAMB231 and HT29 cells transfected with Tgt19 and a decrease in expression of α6 and β4 in only MDAMB231 cells.
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Examination of FAP-BKα expressing cells qualitatively by microscopy and quantitatively by flow cytometry showed a substantial and significant decrease in cell surface labeling accompanied by a meager reduction in internal labeling after fsk treatment.
This caused a significant decrease in cell viability compared to pristine surfaces.
After 24 72 h exposure, all treated groups showed a significant decrease in cell viability.
There was also a significant decrease in cell capacitance.
Conversely, culture of HCAECs with CpG DNA for 24 hours resulted in significant decreases in cell surface and culture media TFPI activity (Fig 3, C and D ).
In accordance, TNK2 silencing by siRNA led to a significant reduction in cell surface EGFR and to a concomitant decrease in the migratory and invasive capacity of breast cancer cells.
Compared to transition apices, inflorescence meristems showed a significantly reduced cell proliferation for the PZ (p≤0.01), which was accompanied by a significant decrease in the surface distance between newly emerging primordia (p≤0.001).
In addition, there was a significant decrease in the surface expression of ICAM-1 in TNF-α and IFN-γ treated IκB S32AS36A) super-repressor transduced UCLA-OSCCs (83% decrease) and HOK-16B cells (78% decrease) when compared to EGFP alone transduced cells.
These experiments indicated that PrC binding leads to a significant decrease in the surface hydrophobicity of the protein (Text S1).
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