The phrase "a significant decrease in cell growth" is correct and usable in written English.
It can be used in scientific or medical contexts when discussing the effects of a treatment or condition on cell proliferation.
Example: "The study revealed a significant decrease in cell growth after the application of the new drug."
Alternatives: "a notable reduction in cell growth" or "a marked decline in cell growth."
PRL-3-depleted AML cells showed a significant decrease in cell growth.
Overexpression of ECRG4 in colorectal carcinoma cells led to a significant decrease in cell growth.
Knockdown of either of these components caused a significant decrease in cell growth in FBW7 −/− cells when compared with FBW7 +/+ cells.
In the proliferation assays, transfection of each of the four siRNAs led to a significant decrease in cell growth 120 h after transfection.
These results indicate that TSA potently inhibits the activation of the PI3K/Akt, p38MAPK and ERK1/2 pathways, leading to a significant decrease in cell growth.
Importantly, downregulation of Sox2 using short interfering RNA in isolated Sox2active cells, but not Sox2inactive cells, resulted in a significant decrease in cell growth, invasiveness and tumorigenicity.
In the proliferation assay, there was a small but significant decrease in cell growth (85.3% (P=0.0027) of negative control in T.Tn and 87.2% (P<0.001) in TE2 cells).
At 0.5µM, the cells showed a significant decrease in cell mass (50%), which correlates very well with the stunted growth observed during this study.
In this study, the sequence-specific inhibition of mutant KrasG12D allele resulted in a significant decrease in tumour cell growth and an altered morphology and clonogenic ability.
The shECT2-transfected cells showed a significant decrease in cellular growth compared with Mock-transfected cells (Figure 5).
The shCDCA3-transfected H1 and Sa3 cells showed a significant decrease in cellular growth compared with mock-transfected cells (* p < 0.05).
