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The phrase "a significant commitment of" is correct and usable in written English.
It can be used when discussing the allocation of resources, time, or effort towards a particular goal or project.
Example: "The organization made a significant commitment of funds to support the new initiative aimed at improving community health."
Alternatives: "a considerable investment of" or "a substantial dedication of".
Exact(14)
Dining at Perla takes a significant commitment of time and money.
Although insider trading is not a particularly complex crime, proving the case still requires a significant commitment of resources.
But at least the response to the Ebola crisis in west Africa by the US, Britain and France now involves a significant commitment of people and resources.
Mr. DiMasi, in an interview last week, said: "I see a significant commitment of businesses to contribute in some way to the insurance costs of the uninsured.
City Councilman Simcha Felder, who accompanied Mr. Bloomberg, said it took a significant commitment of time and energy for the mayor to come here.
"So if they make a significant commitment of money without knowing if this is going to meet their obligation, they're taking a risk".
Similar(45)
This means that running for reelection will require--appropriately in our democracy--a significant commitment of my time and energy, introducing myself to hundreds of thousands of new constituents, learning about the regional and local issues of concern to them and, not least importantly, raising an additional 1.5 to 2 million dollars.
The treaty represented a significant commitment on the part of more than 140 (now 185) signatory powers to control nuclear weapons proliferation; nevertheless, for many years the treaty, which went into effect in 1970, was not ratified by significant nuclear powers (including China and France) and many "near-nuclear" states (including Argentina, Brazil, Egypt, Israel, Pakistan, and South Africa).
Implementation of PBL can be a daunting task and will require detailed and careful planning, together with a significant commitment on the part of educators given the responsibility to implement PBL in an institution.
NGOs involved in carrying out or sponsoring studies, research, and the publication of other scientific or relevant food safety literature can demonstrate a significant commitment to the dissemination of this literature through an open access policy, whereby content is freely available for people to freely access.
Israel prides itself in being a Jewish state, which implies a significant commitment to the values of Judaism.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com