Sentence examples for a significant clinical problem from inspiring English sources

Cytomegalovirus (CMV) retinitis in patients infected with human immunodeficiency virus (HIV) is a significant clinical problem.

Wear of total hip prosthesis is a significant clinical problem that nowadays involves a growing number of patients.

The diagnosis and treatment of facial deformities, including mandibular asymmetries, can pose a significant clinical problem.

The ability to maintain dialysis patients' hemoglobin (Hgb) within narrow targets remains a significant clinical problem.

Non-epileptic attack disorder (NEAD) poses a significant clinical problem but is poorly understood.

Auto-immune hypophysitis represents a significant clinical problem for several reasons.

Medication nonadherence is a significant clinical problem in chronic disease management.

The recurrence of regurgitation after surgical mitral valve (MV) repair remains a significant clinical problem.

Endocrine therapies are effective in the treatment of hormone receptor (HR -positive breast cancer, HR -positivenovo or acquired treatment resistance is a significant clinical probreast

Diabetic neuropathy is a significant clinical problem that currently has no effective therapy, and in advanced cases, it is a major cause of morbidity and mortality worldwide.

For HR/VHR patients, inability to salvage after relapse (nearly all of which were in the bone marrow) remains a significant clinical problem.