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His medical writings constitute a significant chapter in the history of medical science.
In the Shah's palace of Ali Qapu, the wall paintings in his reception rooms illustrate a significant chapter in the history of globalisation.
"This is a significant chapter in the commission's and the profession's efforts to reinforce the importance of auditor independence," Arthur Levitt, the S.E.C. chairman, said in a statement.
Words such as colonialism, imperialism, jingoism and empire feel awkward and discredited terms that belong to a significant chapter in British history.
The sentencing of Paul Manafort, former chairman of President Trump's campaign, was highly anticipated, capping a significant chapter in Robert S. Mueller III's special counsel investigation.
As we reported in this week's print edition, the death of Emilio Botín, Santander's chairman since 1986, is the end of a significant chapter in the bank's history.
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This is the beginning of a new, significant chapter in the story of the magnetically charged interaction of Michael Flynn and Donald Trump.
Thirty years later, the occupation is still regarded as a highly significant chapter in Scottish labour history.
Workers at a Greenock textile factory have celebrated the 30th anniversary of what is regarded as a highly significant chapter in Scottish labour history.
Senior night closed a significant chapter for Cluess, who was hired in April 2010.
In exchange for averting a small but significant chapter in the ongoing depredation of the planet, Correa requested $3.6 billion — half of the oil's market value at the time.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com