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His medical writings constitute a significant chapter in the history of medical science.
Senior night closed a significant chapter for Cluess, who was hired in April 2010.
In the Shah's palace of Ali Qapu, the wall paintings in his reception rooms illustrate a significant chapter in the history of globalisation.
"This is a significant chapter in the commission's and the profession's efforts to reinforce the importance of auditor independence," Arthur Levitt, the S.E.C. chairman, said in a statement.
Words such as colonialism, imperialism, jingoism and empire feel awkward and discredited terms that belong to a significant chapter in British history.
As we reported in this week's print edition, the death of Emilio Botín, Santander's chairman since 1986, is the end of a significant chapter in the bank's history.
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This is the beginning of a new, significant chapter in the story of the magnetically charged interaction of Michael Flynn and Donald Trump.
In exchange for averting a small but significant chapter in the ongoing depredation of the planet, Correa requested $3.6 billion — half of the oil's market value at the time.
After living in this country as an undocumented immigrant for a decade, this moment represented the end of an arduous but significant chapter that has lasted for much of my life.
In my book All Men Are Jerks until Proven Otherwise, I consider the most significant chapter, "If You Want a Man Get a Life!" This applies to men too.
Her return to Symphony Hall, Birmingham, a concert that was repeated at the Proms in London the following evening, then, was very much a coronation, and the real beginning of what promises to be another hugely significant chapter in Birmingham's musical life.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com