The phrase "a significant change when" is correct and usable in written English.
It can be used to introduce a condition or situation that leads to a notable transformation or alteration.
Example: "There was a significant change when the new policy was implemented, affecting all employees."
Alternatives: "a major shift when" or "a notable transformation when".
We can see clearly a significant change when the barrier changes from transparent to opaque.
They suggest that far away from design point the energy transfer inside the runner suffers a significant change when compared with the normal operation, most of the energy being now transferred on the second pass.
Although the microarray statistical analysis did not show a significant change, when we compared the SAA probe intensities between LPS and control intestines, the LPS-treated animals showed an average intensity 3 times greater than the controls.
The recoveries of ACTR and RS were good and did not show a significant change when the critical parameters were modified.
It is not clear why the difference in r is necessarily interpreted as a significant change when only 30% of the cases are validated.
The expression of the Top1β gene did not show a significant change when 10 nM and 50 nM of Cd were added while when 100 nM was added a 4.0-fold increase was observed.
The porous structure of the calcined catalysts exhibited an significant change when Zr/Al ratio reached 0.5.
These parameters did not display any significant change when the force exerted on bonds varied between 3.5 and 11 pN.
In a period of significant change when contemporary society has demonstrated to be more conscious about the principle of accessibility, being no longer focused on accommodating people with disabilities, the current challenge involves the enhancement of inclusive design development.
Moreover, in the other study, when mitiglinide (30 mg/day) was given concomitantly with voglibose (0.6 mg/day), body weight decreased significantly, whereas there was no significant change when a double dose of mitiglinide was given (60 mg/day).
Akbar Hashemi Rafsanjani, the leading opposition-backed candidate in Iran's presidential election, was disqualified on Tuesday from standing in a blow to those hoping for significant change when Mahmoud Ahmadinejad leaves office.
