The phrase "a significant benefit when" is correct and usable in written English.
It can be used to introduce a condition or situation where a notable advantage is realized.
Example: "Implementing this new software can provide a significant benefit when it comes to improving overall efficiency in the workplace."
Alternatives: "a major advantage when" or "a considerable benefit when".
Certainly, there isn't a significant benefit when people present their passport to a customs official.
Also, Windows 8 resumes in about two seconds, which is a significant benefit when you're on the move.
Instead, it simply ameliorates the illness's highly disruptive symptoms — a significant benefit when the short trip to the bathroom seems like a marathon.
The Fido brand, Mr. Sharwood said, will become a significant benefit when Virgin Mobile, part of the Virgin Group, enters the Canadian market soon through a joint venture with Bell Mobility.
The descriptor-based approach provides a significant benefit when the image quality is poor or the tomato is highly occluded (e.g., sequences 3, 4, 10, 11, 14, 15, 17, 20, 21).
A report said: "The prospect of the availability of the elements of sports and open space to the general public is a significant benefit when compared to the otherwise uncertain future of the site, which may not include public access.
As opposed to IL-17A, even a single systemic administration of 3 µg of IL-23 (intraperitoneal injection) on the day of infection provided a moderate, yet statistically significant, benefit when compared to the control PBS treatment.
In light of these findings, the company regrettably concluded that the efficacy of Justiva may be insufficient to demonstrate significant benefit when tested in a broad population of scar revision patients.
With the exception of renal carcinoma and glioblastoma multiforme [ 8, 9], bevacizumab appears to have little activity as a single agent, although it does confer significant benefit when combined with cytotoxic agents and is now approved by the US Food and Drug Administration for use in colorectal, breast, lung and renal cancer, and glioblastoma multiforme.
Preliminary evidence from this study indicates that these automated MRI measures can identify MCI converters from MCI non-converters with a high degree of accuracy and have significant benefit when compared to clinical and neuropsychological assessments alone for predicting progression from MCI to Alzheimer's disease (Desikan et al., 2009).
This will help to ensure that potentially valuable agents are not discarded because of the inefficacy of a single agent, when these agents could impart clinically significant benefit when used in combination.
