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The phrase "a significant benefit from" is correct and usable in written English.
It can be used when discussing the advantages or positive outcomes derived from a particular action, decision, or situation.
Example: "The new policy has resulted in a significant benefit from increased employee productivity."
Alternatives: "a considerable advantage from" or "a notable gain from".
Exact(56)
By contrast, the airline industry is starting to see a significant benefit from the Web.
Regeneron Pharmaceuticals, a biotechnology company, failed to find a significant benefit from its experimental rheumatoid arthritis medicine in a study.
Only 4percentnt of company bosses said there was a significant benefit from gig economy arrangements.
A significant benefit from this approach is circumvention of gas phase dissolution and diffusion in the liquid phase to reach catalytic sites.
It is clear that only a few of these women gain a significant benefit from this additional therapy, while most suffer its side effects.
There is one more group that would derive a significant benefit from a national ID card -- the millions of law-abiding employers who now have to go through a fairly onerous procedure for every new employee they hire.
Where medium-to-long-term interim storage of wastes is required pending an eventual disposal route, then there is a significant benefit from placing the radioactive materials and wastes into a passively safe form under passively safe conditions.
Similar(4)
Although the database from which these observations are derived represents the largest UK hospital cohort with detailed pre-admission data, it is possible that a significant beneficial effect has been missed and that a larger study could reveal a clinically significant benefit from statin administration.
However, when the comparison was restricted to a group of high-risk patients there was a statistically significant benefit from radiotherapy with respect to loco-regional control (P = 0.03) but not with respect to survival (P = 0.23).
A highly significant benefit from combination chemotherapy was observed in patients with a good performance status (HR = 0.76, p < 0.001).
Although a small benefit cannot be ruled out, the likelihood of a clinically significant benefit from IVIG appears to be low.
More suggestions(15)
a tremendous benefit from
a huge benefit from
a noticeable benefit from
a considerable benefit from
a vast benefit from
a large benefit from
a substantial benefit from
a sizable benefit from
a significant advantage from
a major benefit from
a neurological benefit from
a significant increase from
a significant admission from
a significant raise from
a significant object from
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com